U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ERX11386145: Illumina MiSeq paired end sequencing
1 ILLUMINA (Illumina MiSeq) run: 2.4M spots, 323.9M bases, 200.8Mb downloads

Submitted by: Innstituto de Biomedicina de Valencia
Study: ChIPseq_of_B.subtilis_subtilis_delta6
show Abstracthide Abstract
Arbitrium-coding phages use peptides to communicate and coordinate the decision between lysis and lysogeny. However, the process by which these phages establish lysogeny remains incompletely understood. Here, focusing on the SPbeta phage family's model phages phi3T and SPß, we report that a six-gene operon called the "SPbeta phages repressor operon" (Sro) expresses not one but two master repressors, SroE and SroF, the latter of which folds like classical phage integrases. To promote lysogeny, these repressors bind to multiple places in the phage genome. SroD is an additional auxiliary repressor that, along with SroEF, forms the repression module necessary for lysogeny establishment and maintenance. Additionally, the proteins SroABC within the operon are proposed to constitute the transducer module, connecting the arbitrium communication system to the activity of the repression module. Overall, this research sheds light on the intricate and specialised repression system employed by arbitrium SPß-like phages in making lysis-lysogeny decisions.
Sample: delta6_SroFphi3T_phi3T_Rep1_out
SAMEA114321746 • ERS16310858 • All experiments • All runs
Library:
Instrument: Illumina MiSeq
Strategy: WGS
Source: GENOMIC
Selection: RANDOM
Layout: PAIRED
Runs: 1 run, 2.4M spots, 323.9M bases, 200.8Mb
Run# of Spots# of BasesSizePublished
ERR120018432,444,602323.9M200.8Mb2023-10-25

ID:
30163779

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...